Periodontal tissue engineering: A new paradigm for periodontal regeneration

Regenerative treatment of periodontal defects with an agent, or procedure, requires that each functional stage of reconstruction be grounded in a biologically directed process. With this paradigm, we contended the way of periodontal regeneration through the application of current knowledge in the fields of molecular and cell biology, developmental biology and tissue engineering principles as applicable to tissue engineering. Through a combination of transplanted biomaterials containing appropriately selected and primed cells, together with an appropriate mix of regulatory factors to allow growth and specialization of the cells and matrix, we envision a new vista for periodontal regeneration becoming possible.